Protein Expression and Purification

ATGCell specializes in the expression and purification of recombinant proteins from genetically engineered HEK and CHO cells. We have experience in expressing many different classes of proteins, including cytokines, growth factors, cell surface antigens, kinases, proteases, transcription factors, nuclear hormone receptors, G-protein coupled receptors and ion channels using our propretary mammalian cell expression and purification systems. We offer a comprehensive set of assistances to express and purify your proteins of interest in HEK and/or CHO cells. We are tailored to the specific needs and preferences of our clients regarding cell line epitope-tagging of recombinant proteins, expression analysis, expression optimization, production scale, product purity, and product activity, etc. We also produce proteins under contract for academic research laboratories, and pharmaceutical and biotechnological companies for use in high throughput screening, crystallography, and in vivo studies. ATGCell provides:

  • Rapid turn-around: Weeks instead of months
  • Experience: Hundreds of diverse classes of proteins produced
  • Multiple host cell expression systems: HEK, CHO and/or other client-defined cell lines
  • Capacity: Microgram to gram quantities of purified protein
  • Quality: Batch records and certificates of analysis with every lot
  • Clear communication: Detailed proposals with milestones
  • Customization: Proteins formatted for specific applications
  • Confidentiality: Work performed under strict confidentiality

At ATGCell, we are committed to providing excellent service. We will help you increase your productivity and conserve precious internal resources. Whether you need milligram or gram quantities, think of ATGCell as your first choice for recombinant proteins.

ATGCell also offers E. coli protein expression service. The combined expertise of our technical and scientific staff in cDNA cloning, protein expression/purification allows to assist you with the generation of high-quality recombinant proteins at each and every step: You provide us with the cDNA sequence information of your targets, and we will provide you with the purified proteins in return.

For mammalian cells as expression hosts, price can be as low as $2,500 per gene. Expected turn-around time can be as short as 5-6 weeks.

For bacteria as expression hosts, price can be as low as $1,000 per gene. Expected turn-around time can be as short as 2-3 weeks.

Please contact our experts to discuss you needs.